A recent investment at our Santa Perpetua facility in Spain provided the missing piece of the puzzle in Centrient’s ambition to become 100% PNEC compliant. One of the site’s effluent stream matrixes contained measurable residual antibiotics combined with high concentrations of inorganic salts, making it difficult to treat this stream in a conventional way. To eliminate the residual antibiotics, the Centrient S&PT laboratory developed an innovative solution based on bio-catalysis. The infrastructure for this difficult-to-treat stream was installed to meet the PNEC target value. We are making modifications in another facility to produce the biocatalyst for this purpose. As a result, all our manufacturing sites are now PNEC target-value compliant as per the AMR Industry Alliance.